Tohru Fujiwara Selected Research

X-linked sideroblastic anemia

1/2022	Congenital sideroblastic anemia model due to ALAS2 mutation is susceptible to ferroptosis.
1/2019	Molecular pathophysiology and genetic mutations in congenital sideroblastic anemia.
1/2018	[Molecular pathophysiology of sideroblastic anemia].
1/2018	[Successful treatment of X-linked sideroblastic anemia with ALAS2 R452H mutation using vitamin B6].
2/2015	[Update on the biology of heme synthesis in erythroid cells].
12/2013	Pathophysiology and genetic mutations in congenital sideroblastic anemia.
1/2013	Clinical and genetic characteristics of congenital sideroblastic anemia: comparison with myelodysplastic syndrome with ring sideroblast (MDS-RS).

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Tohru Fujiwara Research Topics

Disease

12	Sideroblastic Anemia 01/2022 - 12/2013
7	X-linked sideroblastic anemia 01/2022 - 01/2013
5	Rare Diseases (Rare Disease) 01/2020 - 12/2013
4	Anemia 01/2018 - 01/2013
4	Hypertension (High Blood Pressure) 04/2003 - 02/2002
3	Myelodysplastic Syndromes (Myelodysplastic Syndrome) 01/2022 - 01/2018
3	Multiple Myeloma 08/2019 - 01/2017
3	Graft vs Host Disease (Graft-Versus-Host Disease) 01/2019 - 09/2004
3	Neoplasms (Cancer) 01/2019 - 01/2007
3	Acute Erythroblastic Leukemia (Erythroleukemia) 01/2019 - 01/2015
2	BCR-ABL Positive Chronic Myelogenous Leukemia (Chronic Myelogenous Leukemia) 06/2022 - 11/2012
2	Hematologic Neoplasms (Hematological Malignancy) 01/2019 - 03/2014
2	Leukemia 01/2019 - 09/2004
2	Inflammation (Inflammations) 10/2018 - 02/2016
2	Acute Myeloid Leukemia (Acute Myelogenous Leukemia) 01/2016 - 08/2005
2	Breast Neoplasms (Breast Cancer) 11/2014 - 05/2010
2	Essential Hypertension 07/2002 - 02/2002
1	Lymphoproliferative Disorders (Lymphoproliferative Disorder) 06/2022
1	Acute Megakaryoblastic Leukemia (Leukemia, Megakaryocytic) 09/2021
1	Germ Cell and Embryonal Neoplasms (Germ Cell Tumor) 09/2021
1	Lung Neoplasms (Lung Cancer) 01/2021
1	VLCAD deficiency 01/2021
1	hereditary Xerocytosis 11/2019
1	Pyruvate Kinase Deficiency of Red Cells 11/2019
1	Diamond-Blackfan Anemia (Anemia, Diamond Blackfan) 11/2019
1	Aplastic Anemia (Anemia, Hypoplastic) 01/2019
1	Residual Neoplasm 01/2019
1	Precursor B-Cell Lymphoblastic Leukemia-Lymphoma (Leukemia, Pre B Cell) 01/2019
1	T-Cell Leukemia (Leukemia, T Cell) 01/2019
1	Myeloid Leukemia (Leukemia, Myelocytic) 01/2019
1	Iron Overload 01/2018
1	Iron Deficiencies 01/2017
1	Iron-Deficiency Anemia (Anemia, Iron Deficiency) 01/2017
1	Essential Thrombocythemia 08/2016
1	Mitochondrial Diseases (Mitochondrial Disease) 02/2016
1	Virus Diseases (Viral Diseases) 01/2016
1	Porphyrias (Porphyria) 02/2015
1	Erythropoietic Protoporphyria 02/2015
1	Hematologic Diseases (Blood Diseases) 03/2014
1	Chronic Disease (Chronic Diseases) 01/2013
1	Hematoma 01/2013

Drug/Important Bio-Agent (IBA)

10	Heme (Haem)IBA 01/2020 - 12/2013
8	IronIBA 01/2020 - 12/2013
5	SulfurIBA 01/2020 - 12/2013
5	Mitochondrial Proteins (Mitochondrial Protein)IBA 01/2020 - 12/2013
5	EnzymesIBA 11/2019 - 12/2013
4	CytokinesIBA 02/2016 - 01/2013
3	CalciumIBA 01/2021 - 02/2002
2	5-Aminolevulinate SynthetaseIBA 01/2022 - 02/2014
2	RNA Splicing FactorsIBA 01/2022 - 01/2020
2	Glucose (Dextrose)FDA LinkGeneric 01/2021 - 11/2019
2	Phosphates (Orthophosphate)IBA 01/2021 - 11/2019
2	AcidsIBA 01/2019 - 11/2014
2	GlobinsIBA 01/2017 - 01/2017
2	Angiotensin-Converting Enzyme Inhibitors (ACE Inhibitors)IBA 04/2003 - 02/2002
2	Angiotensin Receptor AntagonistsIBA 04/2003 - 02/2002
2	Antihypertensive Agents (Antihypertensives)IBA 05/2002 - 02/2002
1	Plasminogen Activators (Plasminogen Activator)IBA 06/2022
1	Hormones (Hormone)IBA 01/2021
1	Mitochondrial DNA (mtDNA)IBA 01/2021
1	Membrane Proteins (Integral Membrane Proteins)IBA 11/2019
1	Adenylate KinaseIBA 11/2019
1	IsomerasesIBA 11/2019
1	daratumumabIBA 08/2019
1	Methotrexate (Mexate)FDA LinkGeneric 01/2019
1	Antilymphocyte Serum (Anti-Thymocyte Globulin)IBA 01/2019
1	Mycophenolic Acid (Cellcept)FDA LinkGeneric 01/2019
1	PorphyrinsIBA 01/2019
1	Photosensitizing Agents (Photosensitizers)IBA 01/2019
1	gamma-Aminobutyric Acid (GABA)IBA 01/2019
1	Tacrolimus (Prograf)FDA LinkGeneric 01/2019
1	Transcription Factors (Transcription Factor)IBA 10/2018
1	Aminolevulinic Acid (Levulan)FDA Link 05/2018
1	Hemoglobins (Hemoglobin)IBA 01/2018
1	Folic Acid (Vitamin M)FDA LinkGeneric 01/2018
1	Vitamin B 6IBA 01/2018
1	CopperIBA 01/2018
1	VitaminsIBA 01/2018
1	Heme Oxygenase-1IBA 01/2017
1	proto-oncogene protein Spi-1IBA 01/2017
1	Lysophosphatidic Acid ReceptorsIBA 01/2017
1	ChromatinIBA 01/2017
1	anagrelide (Agrylin)FDA LinkGeneric 08/2016
1	InflammasomesIBA 02/2016
1	Interleukin-1 (Interleukin 1)IBA 02/2016
1	PotassiumIBA 02/2016
1	Reactive Oxygen Species (Oxygen Radicals)IBA 02/2016
1	Small Interfering RNA (siRNA)IBA 01/2015
1	Thymic Stromal LymphopoietinIBA 11/2014
1	3-deazaneplanocinIBA 03/2014
1	MethyltransferasesIBA 03/2014
1	S-Adenosylmethionine (Ademetionine)IBA 03/2014
1	Messenger RNA (mRNA)IBA 02/2014
1	HepcidinsIBA 01/2013
1	DNA (Deoxyribonucleic Acid)IBA 01/2013
1	K 7174IBA 01/2013

Therapy/Procedure

5	Therapeutics 08/2019 - 02/2002
4	Transplantation 06/2022 - 04/2004
3	Stem Cell Transplantation 06/2022 - 04/2004
3	Hematopoietic Stem Cell Transplantation 09/2021 - 09/2004